"MINIMUM ORDER: 5 vials (250 assays)"

Each kit includes:

• Vials of dried, pre-mixed substrate and internal standard (qNMR quantified) for MS/MS enzyme assay of Galactosylceramidase (GALC).

• The relevant Enzyme Assay Buffer.

First order comes with qNMR quantified enzymatic product relevant to the GALC enzyme assay, for mass spectrometry tuning and standard curve generation (See Absolute Quantification).

Krabbe

Galactosylceramidase Assay Kit

SKU: CS9B

Catalog Number: CS9B
Li, Y., Scott, C.R., Chamoles, N.A., Ghavami, A., Pinto, B.M., Turecek, F. and Gelb, M.H., 2004. Direct multiplex assay of lysosomal enzymes in dried blood spots for newborn screening. Clinical chemistry, 50(10), pp.1785-1796. DOI: 10.1373/clinchem.2004.035907

Zhang, X.K., Elbin, C.S., Turecek, F., Scott, R., Chuang, W.L., Keutzer, J.M. and Gelb, M., 2009. Multiplex lysosomal enzyme activity assay on dried blood spots using tandem mass spectrometry. In Clinical Applications of Mass Spectrometry: Methods and Protocols (pp. 339-350). Totowa, NJ: Humana Press. DOI: 10.1007/978-1-60761-459-3_32

Spacil, Z., Tatipaka, H., Barcenas, M., Scott, C.R., Turecek, F. and Gelb, M.H., 2013. High-throughput assay of 9 lysosomal enzymes for newborn screening. Clinical chemistry, 59(3), pp.502-511. DOI: 10.1373/clinchem.2012.189936

Elliott, S., Buroker, N., Cournoyer, J.J., Potier, A.M., Trometer, J.D., Elbin, C., Schermer, M.J., Kantola, J., Boyce, A., Turecek, F. and Gelb, M.H., 2016. Pilot study of newborn screening for six lysosomal storage diseases using Tandem Mass Spectrometry. Molecular genetics and metabolism, 118(4), pp.304-309. DOI: 10.1016/j.ymgme.2016.05.015

Elliott, S., Buroker, N., Cournoyer, J.J., Potier, A.M., Trometer, J.D., Elbin, C., Schermer, M.J., Kantola, J., Boyce, A., Turecek, F. and Gelb, M.H., 2016. Dataset and standard operating procedure for newborn screening of six lysosomal storage diseases: By tandem mass spectrometry. Data in brief, 8, pp.915-924. DOI: 10.1016/j.dib.2016.06.052

Galactosylceramidase Assay Kit

PRODUCT INFO

RELEVANT LITERATURE

SOP

SDS