This product is currently being modified and replaced with a QC DBS Calibrator set. The new product will be matched to the previous batches of this product. At this point in time we have limited stock of this product. Prior to ordering, please contact us at contact@enfanos.com. Thank you!
Endogenous Glycosaminoglycan (GAG) Disaccharide, "UA-HNAc(1S)-Late" prepared with blood from a healthy adult. Product consists of one QC High DBS card prepared with blood from a healthy adult spiked with the Endogenous Disaccharide, "UA-HNAc(1S)-Late." One control DBS card prepared with unspiked blood is also provided. Each DBS card contains ten DBS. At least six 3 mm punches can be taken from each DBS.
*The Endogenous GAG Disaccharide, "UA-HNAc(1S)-Late," was described by Herbst et. al. as being elevated in 18 MPS-II Newborn DBS (I2S deficiency) when compared to a reference range of healthy newborns and newborns with I2S Pseudodeficiencies.
Internal Standard sold separately (product BM14A).
Endogenous GAG NRE Biomarker "UA-HNAc(1S)-Late" QC DBS
Herbst, Z.M., Urdaneta, L., Klein, T., Burton, B.K., Basheeruddin, K., Liao, H., Fuller, M., Gelb, M.H., 2022. Evaluation of Two Methods for Quantification of Glycosaminoglycan Biomarkers in Newborn Dried Blood Spots from Patients with Severe and Attenuated Mucopolysaccharidosis Type II. International Journal of Neonatal Screening, 8(1), p.9.
https://doi.org/10.3390/ijns8010009